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Prediction possible about miscarriage after in vitro pregnancy

Marian Chu  Published 2017.08.07  15:32  Updated 2017.08.07 16:51

공유
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A Korean research team of two university hospitals has discovered a method to predict miscarriages in women with previous miscarriages following in vitro pregnancies.

Professors Shin Jung-ho (left) and Kim Yong-jin of Korea University Guro Hospital presented findings that progesterone levels can predict miscarriages in women who have had them previously after in vitro fertilization.

Researchers from Korea University Guro Hospital고대구로병원 and Seoul National University Hospital서울대병원 conducted a study on 148 women who have experienced two or more unexplained miscarriages after in vitro fertilizations.

The findings showed women who had less than 25 ng/mL blood progesterone concentration levels had a higher probability of having a miscarriage.

Notably, the study found women with a blood progesterone concentration of 25ng/mL or more had a pregnancy maintenance rate of 98 percent. The numbers fell by more than half (41.8 percent) in women who had a blood progesterone concentration of less than 25ng/mL.

The findings suggest that blood progesterone concentration should be above 25ng/mL to significantly lower the risk of miscarriage.

“Although we have known progesterone is a hormone that plays a significant role in pregnancy, we had no accurate figures to predict successful pregnancies until now,” said Professor Kim Yong-jin김용진 of Korea University Guro Hospital. “This study suggests blood progesterone concentration of 25 ng/mL can be an explicit reference for predicting early miscarriages, which will be helpful in the initial treatment and follow-up studies.”

The study – conducted by Korea University Guro Hospital’s Kim Yong-jin and Shin Jung-ho신정호 and Seoul National University Hospital’s Ku Seung-yup구승엽 – was published in the July edition of the international journal, PLOS ONE.

yjc@docdocdoc.co.kr

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